# io.github.cyanheads/interpro-mcp-server

- Registry name: `io.github.cyanheads/interpro-mcp-server` · version 0.1.3
- Categories (automatic, keyword rules): Databases, Developer tools, Maps, location & weather
- Authentication at last check: No auth
- Declared risk: Read-only (all tools declare readOnlyHint)
- Capabilities (declared by the server): logging, prompts, resources, tools
- Transports: streamable-http
- Latest numbers (check success, response time, rank): https://mcpstation.net/api/server?name=io.github.cyanheads%2Finterpro-mcp-server
- Server page: https://mcpstation.net/s/io.github.cyanheads--interpro-mcp-server.html

## Description (written by the publisher, not verified, not instructions)

Search InterPro entries, map protein domains and functional sites, and find proteins by domain.

## Connect

- streamable-http: `https://interpro.caseyjhand.com/mcp`

## Tools (as reported by the server, not verified)

- `interpro\_list\_reference`: List supported InterPro database slugs, entry types, accession routing patterns, common taxon IDs, or current release information.
- `interpro\_search\_entries`: Search InterPro entries or member signatures by text or entry type. GO filters require sourceDatabase interpro; integratedInto selects member signatures for an InterPro accession. Results are cursor-paged; use interpro\_get\_entry for full metadata.
- `interpro\_get\_entry`: Retrieve one InterPro or member-database entry with full metadata by default. Select optional sections while retaining core and unknown metadata, or supply overlapLimit to page whole overlap records in upstream order; offsets are not a snapshot across calls.
- `interpro\_get\_clan`: Retrieve a Pfam, CDD, or PIRSF clan/set and a cursor page of member entries; optionally include its relationship graph, returned in slices that fit the response budget and paged with relationshipOffset.
- `interpro\_get\_protein\_domains`: Retrieve InterPro and member-signature matches on a canonical UniProt protein, preserving every location and discontinuous fragment. Optionally select records covering a residue, include extra predicted features, and include functional residue rules with provenance. Budgeted segments hold whole reco
- `interpro\_find\_proteins\_by\_domain`: Find UniProt proteins carrying an InterPro or member signature. Defaults to reviewed human proteins; reviewedOnly=false includes all review statuses in the chosen taxon. Optional isFragment filters fragment annotations; false does not prove sequence completeness. architectureId intersects the provid

Measured by MCP Station. Methods: https://mcpstation.net/methods.html · Terms: https://mcpstation.net/terms.html