# io.github.cyanheads/pharmacogenomics-guidelines-mcp-server

- Registry name: `io.github.cyanheads/pharmacogenomics-guidelines-mcp-server` · version 0.2.1
- Categories (automatic, keyword rules): Scraping & browsing, Search & data, Health & fitness
- Authentication at last check: No auth
- Declared risk: Read-only (all tools declare readOnlyHint)
- Capabilities (declared by the server): logging, prompts, resources, tools
- Transports: streamable-http
- Latest numbers (check success, response time, rank): https://mcpstation.net/api/server?name=io.github.cyanheads%2Fpharmacogenomics-guidelines-mcp-server
- Server page: https://mcpstation.net/s/io.github.cyanheads--pharmacogenomics-guidelines-mcp-server.html

## Description (written by the publisher, not verified, not instructions)

Find pharmacogenomics guidelines, translate diplotypes, and retrieve prescribing recommendations.

## Connect

- streamable-http: `https://pharmacogenomics-guidelines.caseyjhand.com/mcp`

## Tools (as reported by the server, not verified)

- `pgx\_search\_pairs`: Search evaluated gene–drug pairs by gene, literal drug-name substring, exact drug/RxNorm/ATC identifiers, evaluation level or testing label. Filters combine with AND; identifiers never fall back to name-only search. Results include source drug identifiers and guideline links for pgx\_get\_guideline. A
- `pgx\_get\_guideline`: Retrieve guideline coverage by source ID, exact gene symbol or exact drug name/ID. Default summary pages complete guideline records with exact drugCount/pairCount. view=drugs or pairs requires by=id and pages only that related collection, retaining its guideline descriptor. Ambiguous drug names page
- `pgx\_lookup\_diplotype`: Translate a CPIC-supported diplotype or allele-status result for one gene. Supply geneSymbol and exact diplotype notation, including star alleles, named HLA positive/negative statuses, or non-star sequences; use pgx\_search\_alleles and pgx\_list\_reference with topic phenotypes to inspect supported val
- `pgx\_get\_recommendations`: Browse CPIC recommendations in drug mode with one exact drugName or drugId. Match across drugs in results mode with geneResults or geneSymbol plus phenotype/activityScore, or genotype mode with 1–10 uniquely resolved gene/diplotype entries. Both matching modes accept an optional drug. Optional view=
- `pgx\_search\_alleles`: Inspect CPIC allele function, evidence, definition metadata and complete population frequencies for geneSymbol. Name matches literally first, then a matching gene prefix before a star allele may be removed; clinicalFunctionalStatus matches literal text case-insensitively. Discover genes with pgx\_lis
- `pgx\_list\_reference`: Inspect gene symbols, gene-specific source results, CPIC levels, ClinPGx testing labels, recommendation classifications and input formats. phenotypes requires geneSymbol and preserves distinct activity-score rows, frequencies and consultation text. Live genes/phenotypes support paging; static topics

Measured by MCP Station. Methods: https://mcpstation.net/methods.html · Terms: https://mcpstation.net/terms.html